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Liranaftate

CAS No. : 88678-31-3

MCE 国际站：Liranaftate

产品活性：Liranaftate (Piritetrate) 是一种具有抗真菌活性的角鲨烯环氧酶抑制剂。Liranaftate 可用于皮肤癣菌的研究。Liranaftate 还能抑制真菌元素促进的 IL-8 产生和实验性炎症。

研究领域：Anti-infection

作用靶点：Fungal

In Vitro: Liranaftate showed excellent fungistatic activity against the conidia of T. rubrum. For each of these agents, the MIC after 14 days of contact was 0.009 g/ml. The liranaftate-induced decrease in the MCC occurred from 9 days onwards; MCC at 14 days was 0.039 g/ml [1]. In time-kill studies, liranaftate showed the greatest decrease to a below detection limit in viable counts of T rubrum. The degree of killing of the strain by amorolfine was not greater than that seen by liranaftate, and little reduction of the viable counts by luliconazole and ketoconazole was observed irrespective of concentrations of the agents [2].

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