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SEMBL

CAS No. : 1443448-82-5

MCE 国际站：SEMBL

产品活性：SEMBL 是一种有效的 NF-κB 抑制剂。SEMBL 能够抑制 NF-κB-DNA 结合，还抑制 NF-κB 依赖性炎性细胞因子分泌。SEMBL 通过降低 MMP 表达来抑制癌细胞的迁移和侵袭。可用于抗癌研究。

研究领域：NF-κB  |  Metabolic Enzyme/Protease

作用靶点：NF-κB  |  MMP

In Vitro: SEMBL inhibits MMP-2 expression and cellular metastatic activity in ovarian carcinoma cells.
SEMBL inhibits the cell-free DNA binding of NF-κB in the ES-2 nuclear extract and inhibits the constitutively activated NF-κB activity in ovarian carcinoma cells.
SEMBL inhibits cellular migration, invasion and MMP-2 expression in ovarian carcinoma cells at non-toxic concentrations.

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