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Luteinizing Hormone Releasing Hormone (LH-RH), salmon

CAS No. : 86073-88-3

MCE 国际站：Luteinizing Hormone Releasing Hormone (LH-RH), salmon

产品活性：Luteinizing Hormone Releasing Hormone (LH-RH), salmon (Salmon GnRH) 是在下丘脑中合成的垂体前体十肽，在控制生殖功能中起关键作用。

研究领域：Others

作用靶点：Others

In Vitro: Luteinizing hormone-releasing hormone (LHRH) is the key hormone in the control of reproductive functions.LHRH acts as an antimitogenic factor through the activation of the Gi-cAMP intracellular signaling pathway. LHRH might act as an inhibitory factor on both cell proliferation and metastatic behavior in melanoma cells. The hypothalamic decapeptide luteinizing hormone-releasing hormone (LHRH) plays a central role in the control of reproduction by stimulating the release of pituitary luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which in turn promote gonadal functions and regulate sex steroid secretion. The effects of LHRH are mediated by high-affinity G protein-coupled LHRH-receptor (LHRH-R) on pituitary gonadotropes. The responses to LHRH vary under different conditions and critically depend on the regimens of administration and doses delivered to gonadotrope cells.

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