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CAS No. : 1401-55-4
MCE 国际站:Tannic acid
产品活性:Tannic acid 是一种新型的 hERG 通道阻塞剂,其IC50 值为 3.4 μM。
研究领域:Membrane Transporter/Ion Channel
作用靶点:Potassium Channel
结构分类:酚类 | 多酚类 | 酮、醛、酸 | 结构分类
来源:植物 | 百合科 | 玉竹
In Vivo: During the course of treatment, tannic acid significantly ameliorates these phenotypes in AD skin lesions. Tannic acid treatment aslo reduces these dermal changes compare with AD mice. Treatment with tannic acid increases PPARγ expression in AD skin sections. The PPARγ protein expression is suppressed in vehicle-treated AD mice, but when treats with tannic acid, its expression is increased dramatically. The IL-1β, TNFα, TNFR1, and COX2 protein expressions are significantly up-regulated in vehicle-treated AD mice, but significantly suppressed by tannic acid treatment.
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