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CAS No. :
MCE 国际站:γ-1-Melanocyte Stimulating Hormone (MSH), amide
产品活性:γ-1-Melanocyte Stimulating Hormone (MSH), amide 是一种含 11 个氨基酸的多肽。γ-1-Melanocyte Stimulating Hormone 通过激活黑皮质素受体 3 (MC3-R) 来调节钠 (Na+) 平衡和血压。
研究领域:GPCR/G Protein | Neuronal Signaling
作用靶点:Melanocortin Receptor
In Vitro: γ-Melanocyte Stimulating Hormone (γ-MSH) regulates a multitude of metabolic functions including energy homeostasis, food intake, sodium (Na+) balance, and blood pressure regulation. γ-MSH is processed from the precursor hormone pro-opio-melanocortin (POMC) in the pituitary gland, where component peptides are released into the cerebral spinal fluid and systemic circulation. The natural receptor for γ-MSH is the melanocortin receptor 3 (MC3-R), a G-protein-coupled receptor that activates adenylate cyclase and is expressed in brain (hypothalamus, cortex, and thalamus), gut, placenta, and kidney. γ-MSH regulates Na+ balance by inducing urinary Na+ excretion (natriuresis) under conditions of high dietary salt intake.
相关产品:Bioactive Compound Library Plus | GPCR/G Protein Compound Library | Neuronal Signaling Compound Library | Endocrinology Compound Library | Anti-Obesity Compound Library | Peptide Library | Membrane Protein-targeted Compound Library | Membrane Receptor-targeted Compound Library | PG106 | Bremelanotide | ACTH (3-24) (human, bovine, mouse, ovine, porcine, rabbit, rat) | ACTH (11-24) | Adrenocorticotropic Hormone (ACTH) (1-39), human(TFA) | MK-0493 | HS024 | Melanotan I acetate | Agouti-related Protein (AGRP) (83-132) Amide (human) | JNJ-10229570 | MCL0020 | MC-4R Agonist 1 | HS014 | [D-Trp8]-γ-MSH | (D-Phe7)-α-MSH | PG-931 | JKC363 | (-)-Isodocarpin | SHU 9119 | Adrenocorticotropic Hormone (ACTH) (1-39), rat | CCZ01048 TFA | β-Melanocyte Stimulating Hormone (MSH), human TFA | RO27-3225 TFA | ACTH (1-17) (TFA) | Terrein | γ1-MSH TFA
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