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Ginsenoside Rg6

CAS No. : 147419-93-0

MCE 国际站：Ginsenoside Rg6

产品活性：Ginsenoside Rg6 在 HepG2 细胞中抑制 TNF-α 诱导的 NF-κB 转录活性， IC₅₀ 为 29.34 μM。Ginsenoside Rg6 还具有细胞凋亡诱导作用。

研究领域：NF-κB  |  Apoptosis

作用靶点：NF-κB  |  Apoptosis

结构分类：萜类  |  三萜

来源：植物  |  五加科  |  人参

In Vitro: Ginsenoside Rg6 inhibits TNF-α-induced NF-κB transcriptional activity with an IC₅₀ of 25.12±1.04 μM in SK-Hep1 cells, consistent with the data from HepG2 cells. Ginsenoside Rg6 exhibits obvious anti-proliferative and apoptosis-inducing effects when it is applied to JK cells in vitro. Ginsenoside Rg6 blocks S arrest in the cell cycle. CCK-8 method shows that after Ginsenoside Rg6 is used, several groups with different concentrations obviously inhibits JK cell proliferation in human lymphocytoma, with evident dose dependency. Based on IC₅₀, the median inhibitory concentration of Ginsenoside Rg6 is 83.08 μM.

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