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Catalpol

CAS No. : 2415-24-9

MCE 国际站：Catalpol

产品活性：Catalpol (Catalpinoside)，是一种在 Rehmannia glutinosa 中发现的鸢尾花苷，具有神经保护，降血糖，抗炎，抗癌，抗痉挛，抗氧化和抗 HBV 的作用。

研究领域：Anti-infection

作用靶点：HBV

结构分类：萜类  |  环烯醚萜

来源：植物  |  玄参科  |  地黄

In Vitro: Catalpol (0.1 μg/mL; for 3 days) can induce neuronal differentiation in PC12 cells through activation of the intracellular signal transduction pathway, and promote neurite length.

In Vivo: Catalpol (25-100 mg/kg; intraperitoneal injection; once) treatment clearly reduces blood urea nitrogen, serum creatinine levels and the expression of KIM-1 in renal ischemia/reperfusion-injury (IRI) mice. Catalpol markedly reduces the expression of PI3K, Akt and eNOS levels, and suppresses the TNF-α, IL-1β, IL-6 and IL-10 activities.

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