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Calycosin-7-O-β-D-glucoside

CAS No. : 20633-67-4

MCE 国际站：Calycosin-7-O-β-D-glucoside

产品活性：Calycosin-7-O-β-D-glucoside 是从黄芪中分离得到的一种异黄酮。Calycosin-7-O-β-D-glucoside 具有多种生物活性，如神经保护、心脏保护、抗炎和抗氧化作用。

研究领域：Immunology/Inflammation  |  NF-κB  |  Metabolic Enzyme/Protease

作用靶点：Reactive Oxygen Species

结构分类：黄酮类  |  异黄酮  |  酚类  |  单酚类  |  结构分类

来源：植物  |  豆科  |  蒙古黄芪

In Vitro: Calycosin-7-O-β-D-glucoside (2 μM; 6 hours) remarkably inhibits the expression and activities of MMPs, and secures the expression of cav-1 and tight junction proteins in the microvessels isolated from ischemic rat cortex.

In Vivo: Calycosin-7-O-β-D-glucoside (intraperitoneal injection; 26.8 mg/kg; 14 days) significantly reduces infarct volume, histological damage and BBB permeability in the in vivo MCAO ischemia-reperfusion rat model.

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