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CAS No. : 12583-68-5
MCE 国际站:Parathyroid Hormone (1-34), bovine
产品活性:Parathyroid Hormone (1-34), bovine 是一种有效的甲状旁腺激素 (PTH) 受体激动剂。Parathyroid Hormone (1-34), bovine 增加钙和无机磷酸盐的水平。Parathyroid Hormone (1-34), bovine 可用于研究骨质疏松症。
研究领域:Vitamin D Related/Nuclear Receptor
作用靶点:Thyroid Hormone Receptor
In Vitro: Parathyroid Hormone (1-34), bovine (0.1-100 ng/mL; 2-20 days) are added to the medium, it inhibits osteoblast proliferation in a dose-dependent manner. In another group, bPTH are added to the culture medium from day 1 to day 10, but not from days 11 to 20, a rebound of proliferation is observed in the PTH Day 1–10 group after bPTH withdrawal.Parathyroid Hormone (1-34), bovine (0.1-100 ng/mL; 2-20 days) induces diverse effects on the calcium and phosphorus content of culture medium. The calcium and phosphorus content of culture medium in the PTH-C 100 ng/mL group are higher than in teh control group.
In Vivo: Parathyroid Hormone (1-34)(subcutaneous injection; 80 μg/kg; 5 days) increases serum osteocalcin concentrations without changing serum inorganic phosphate or calcium concentrations in either group of old animals. Serum 1,25-dihydroxyvitamin D concentrations are significantly higher in the PTH-treated senile female rats than the sex-matchedvehicle-treated controls.
相关产品:Bioactive Compound Library Plus | Peptide Library | Taltirelin acetate | [Phe2]-TRH | Parathyroid hormone (1-34) (rat) acetate | Debutyldronedarone hydrochloride | Human PTH-(1-31) | Liothyronine (GMP) | Thyroxine sulfate | TR antagonist 1 | KB130015 | Parathyroid Hormone (1-34), bovine TFA | Protirelin | (D-Trp12,Tyr34)-pTH (7-34) amide (bovine) | PCO371 | Human PTH-(1-31) amide | Tiratricol | GC 14 | KAT681 | Liothyronine | Resmetirom | TRβ agonist 1 | Thyroxine hydrochloride-13C6 | AH3960 | L-Thyroxine-13C6 | 1α-Hydroxy-3-epi-vitamin D3 | Sobetirome | NH-3 | Eneboparatide acetate
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