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Euscaphic acid

CAS No. : 53155-25-2

MCE 国际站：Euscaphic acid

产品活性：Euscaphic acid 是源于 R. alceaefolius Poir 的三萜，DNA polymerase 抑制剂。Euscaphic acid 抑制小牛 DNA 聚合酶 α (pol α) 和大鼠 DNA 聚合酶 β (pol β) 的 IC₅₀值分别为 61 和 108 μM。Euscaphic acid 诱导细胞凋亡 (apoptosis)。

研究领域：Cell Cycle/DNA Damage  |  PI3K/Akt/mTOR  |  Apoptosis

作用靶点：DNA/RNA Synthesis  |  PI3K  |  Apoptosis

结构分类：萜类  |  三萜

来源：植物  |  其他科

In Vitro: Euscaphic acid induces apoptosis and cell cycle arrest in NPC cells by suppression of the PI3K/AKT/mTOR signaling pathway.

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