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Convallatoxin

CAS No. : 508-75-8

MCE 国际站：Convallatoxin

产品活性：Convallatoxin 是从 Adonis amurensis Regel et Radde 分离得到的强心苷。Convallatoxin 通过激活 PPARγ 和抑制 NF-κB 改善结肠炎。Convallatoxin 是一种 P-糖蛋白 (P-gp) 底物，并识别 Val982 是参与其转运的重要氨基酸。Convallatoxin 是配体诱导的 MOR 胞吞作用的增强剂，具有很高的效力和功效。具有抗炎和抗增殖特性。

研究领域：Cell Cycle/DNA Damage  |  Vitamin D Related/Nuclear Receptor  |  NF-κB  |  Membrane Transporter/Ion Channel

作用靶点：PPAR  |  NF-κB  |  P-glycoprotein

结构分类：萜类  |  三萜  |  结构分类

来源：植物  |  毛茛科  |  侧金盏花

In Vitro: Convallatoxin induces HaCaT cell necroptosis.

In Vivo: Convallatoxin exerts antipsoriatic activities in two mouse models of psoriasis.

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