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Nerol

CAS No. : 106-25-2

MCE 国际站：Nerol

产品活性：Nerol 是橙花油的一种成分, Nerol 通过增强 Ca²⁺ 和 ROS 来触发线粒体功能障碍并诱导凋亡。具有抗真菌活性。

研究领域：Immunology/Inflammation  |  NF-κB  |  Metabolic Enzyme/Protease  |  Anti-infection  |  Apoptosis

作用靶点：Reactive Oxygen Species  |  Fungal  |  Mitochondrial Metabolism  |  Apoptosis  |  Endogenous Metabolite

结构分类：其他类

来源：植物  |  其他科

In Vitro: Nerol induces apoptosis associated with the generation of ROS and Ca²⁺ overload in saprotrophic fungus Aspergillus flavus.
The antifungal activity of Nerol (NEL) against Candida albicans, a pathogenic fungus, has a minimum inhibitory concentration (MIC) of 4.4μM that causes noteworthy candidacidal activity through an apoptosis-like mechanism.
Nerol triggers mitochondrial dysfunction and disruption via elevation of Ca²⁺ and ROS in Candida albicans.

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