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Specnuezhenide

CAS No. : 39011-92-2

MCE 国际站：Specnuezhenide

产品活性：Specnuezhenide ((8E)-Nuezhenide) 是从女贞子的果实中分离出来的。Specnuezhenide ((8E)-Nuezhenide) 可通过抑制 NF-κB 和 wnt/β-catenin 信号传导来抑制 IL-1β 诱导的软骨细胞炎症。Specnuezhenide ((8E)-Nuezhenide) 可在骨关节炎 (OA) 大鼠模型中发挥抗炎作用。

研究领域：NF-κB  |  Stem Cell/Wnt

作用靶点：NF-κB  |  Wnt

结构分类：萜类  |  环烯醚萜  |  酚类  |  单酚类

来源：植物  |  木犀科  |  女贞

In Vitro: Specnuezhenide (0.2-5.0 μg/mL) significantly decreases the mRNA expression of VEGFA induced by CoCl2 as a dose-dependent manner in ARPE-19 cells.

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