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α-Linolenic acid

CAS No. : 463-40-1

MCE 国际站：α-Linolenic acid

产品活性：α-Linolenic acid 是从紫苏中分离的，人体无法合成的必需脂肪酸。α-Linolenic acid 可通过调节 PI3K/Akt 信号传导来影响血栓形成过程。α-Linolenic acid 具有抗心律失常的特性，并且与心血管疾病和癌症等有关。

研究领域：PI3K/Akt/mTOR

作用靶点：PI3K  |  Akt

结构分类：其他类

来源：植物  |  菊科  |  短莛飞蓬  |  植物  |  唇形科

In Vitro: α-Linolenic acid converses into the longer chain fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA).

In Vivo: α-Linolenic acid (50, 100, 250 mg/kg; for 10 days) can completely inhibit collagen- and adrenaline-induced thrombosis in mice at 250 mg/kg.
α-Linolenic acid (35, 70, 175 mg/kg) suppresses A-V thrombus formation in rats (weighing at 250 ~ 300 g).
α-Linolenic acid (70 or 175 mg/kg) inhibits collagen stimulated platelet aggregation in rats.

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