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Ferulenol

CAS No. : 6805-34-1

MCE 国际站：Ferulenol

产品活性：Ferulenol，倍半萜烯丙基香豆素衍生物，在泛醌循环水平上特异性抑制琥珀酸泛醌还原酶。 Ferulenol 具有良好的抗分枝杆菌活性和止血作用。

研究领域：Metabolic Enzyme/Protease

作用靶点：Mitochondrial Metabolism

结构分类：苯丙素类  |  香豆素

来源：植物  |  其他科

In Vitro: Ferulenol inhibits the oxidative phosphorylation process by interacting with adenine nucleotide translocase (ANT) and the complex II of the respiratory chain. At low concentrations, ferulenol inhibited ATP synthesis by inhibition of the adenine nucleotide translocase without limitation of mitochondrial respiration. At higher concentrations, ferulenol inhibited oxygen consumption. Ferulenol caused specific inhibition of succinate ubiquinone reductase without altering succinate dehydrogenase activity of the complex II. Ferulenol inhibits succinate ubiquinone reductase(SQR) activity in a concentration-dependent manner and is as effective as thenoyltrifluoroacetone (TTFA).

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