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Estradiol

CAS No. : 50-28-2

MCE 国际站：Estradiol

产品活性：Estradiol (β-Estradiol) 是一种类固醇激素和主要的女性性激素。Estradiol 可上调人子宫内膜干细胞 (hEnSCs) 神经标志物的表达并促进其神经分化。Estradiol 可用于癌症、神经退行性疾病和神经组织工程的相关研究。

研究领域：Vitamin D Related/Nuclear Receptor  |  Metabolic Enzyme/Protease  |  Anti-infection

作用靶点：Estrogen Receptor/ERR  |  Endogenous Metabolite  |  Bacterial

结构分类：酚类  |  单酚类  |  甾体类  |  结构分类

In Vitro: Estradiol (10 nM, 7 days) induces neural differentiation and increased neurite branching of human endometrial stem cells (hEnSCs).
Estradiol (17β-estradiol, 10 nM, 7 days) increases the expression of neuron-like cell markers (Tuj-1, nestin and NF-H) in neural-like cells differentiated from hEnSCs.

In Vivo: Estradiol (1 nM, the hippocampal slices from FBN-ARO-KO mice) rescues long-term potentiation (LTP) amplitude.
Estradiol (0.0167 mg, implanted s.c., FBN-ARO-KO mice) rescues the molecular and functional deficits in FBN-ARO-KO mice.

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