MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务。
CAS No. : 2316-26-9
MCE 国际站:3,4-Dimethoxycinnamic acid
产品活性:3,4-Dimethoxycinnamic acid (O-Methylferulic acid) 是从 Securidaca inappendiculata 中提取和纯化的单体。3,4-Dimethoxycinnamic acid 通过 ROS 介导的信号途径对 L-02 细胞发挥抗凋亡作用。
研究领域:Immunology/Inflammation | NF-κB | Metabolic Enzyme/Protease | Anti-infection
作用靶点:Reactive Oxygen Species | Virus Protease
结构分类:苯丙素类 | 简单苯丙素
来源:植物 | 远志科 | 蝉翼藤
In Vitro: 3,4-Dimethoxycinnamic acid (Methyl ferulic acid; 25, 50 and 100 µM) attenuates the ethanol-induced apoptosis of ethanolexposed L-02 cells.
3,4-Dimethoxycinnamic acid (25, 50 and 100 µM) inhibits the expression levels of Nox4 and p22phox in L-02 cells.
3,4-Dimethoxycinnamic acid (25, 50 and 100 µM) treatment attenuates ethanol-induced MAPK phosphorylation in L-02 cells.
3,4-Dimethoxycinnamic acid decreases the expression levels of superoxide dismutase, catalase and phospholipid hydroperoxide gluthione peroxidase, and downregulates the levels of Bax/Bcl-2 and the cleaved forms of caspase-3 in a dose- and time-dependent manner.
相关产品:Natural Product Library Plus | Bioactive Compound Library Plus | Anti-Infection Compound Library | Immunology/Inflammation Compound Library | Metabolism/Protease Compound Library | NF-κB Signaling Compound Library | Stem Cell Signaling Compound Library | Natural Product Library | Anti-Cancer Compound Library | Antiviral Compound Library | Anti-Aging Compound Library | Antioxidant Compound Library | Reprogramming Compound Library | Oxygen Sensing Compound Library | Ferroptosis Compound Library | Medicine Food Homology Compound Library | Pyroptosis Compound Library | Traditional Chinese Medicine Active Compound Library | Anti-Parkinson's Disease Compound Library | Neurodegenerative Disease-related Compound Library | Mitochondria-Targeted Compound Library | Anti-Cancer Natural Product Library | Antiviral Traditional Chinese Medicine Active Compound Library | Anti-inflammatory Traditional Chinese Medicine Active Compound Library | Plant-Sourced Natural Product Library | Mitochondrial Protection Compound Library | D-α-Hydroxyglutaric acid disodium | 8α-Tigloyloxyhirsutinolide 13-O-acetate | SRPIN340 | Anticancer agent 120 | 7-Hydroxy-4-methyl-2(1H)-quinolone | N-tert-Butyl-α-phenylnitrone-d14 | BDP 581/591 NHS ester | Cysteamine-d4 hydrochloride | Aminothiazole | L-Ascorbic acid sodium salt | SP inhibitor 1 | Manganese(salen) chloride | Genkwanin | Hydroxyphenyl Fluorescein | Glucosamine sulfate | Maresin 1 | L-Lysine-15N2 hydrochloride | Berberine | 1,3-Dicaffeoylquinic acid | Aspirin-d4 | Ciprofloxacin | Echinocystic acid | (-)-α-Pinene | Lacto-N-fucopentaose I | Nisoldipine-d6 | 2'-Deoxy-2'-fluoro-l-uridine | Arg-Tyr | LabMol-319 | HKPerox-2 | 3-Indolepropionic acid
热门产品线:重组蛋白 | 化合物库 | 天然产物 | 荧光染料 | PROTAC | 同位素标记物 | 寡核苷酸 | 抗体 | 点击化学
Trending products:Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides | Antibodies | Click Chemistry
品牌介绍:
• MCE (MedChemExpress) 拥有200 多种全球独家化合物库,我们致力于为全球科研客户提供前沿最全的高品质小分子活性化合物;
• 50,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领;
• 产品种类涵盖各种重组蛋白,多肽,常用试剂盒 ,更有 PROTAC、ADC 等特色产品,广泛应用于新药研发、生命科学等科研项目;
• 提供虚拟筛选,离子通道筛选,代谢组学分析检测分析,药物筛选等专业技术服务;
• 设有专业的实验中心和严格的质控、验证体系;
• 提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告,确保产品的高纯度、高品质;
• 产品的生物活性多经各国客户实验验证;
• Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果;
• 专业团队跟踪最新的制药及生命科学研究进展,为您提供全球最新的活性化合物;
• 与世界各大制药公司及知名科研机构建立了长期的合作。