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CAS No. : 1534-35-6
MCE 国际站:Isolithocholic acid
产品活性:Isolithocholic acid (β-Lithocholic acid) 是石胆酸的一种同分异构体。Isolithocholic acid 是一种胆酸,由 Lithocholic acid 或 Lithocholic acid 3α-sulfate 经微生物代谢形成。
研究领域:Metabolic Enzyme/Protease
作用靶点:Endogenous Metabolite
结构分类:甾体类
In Vitro: Isolithocholic acid at 0.01 % does not inhibit spore germination and outgrowth of CF5 and M120, but it significantly inhibits at the higher concentration (0.1 %). Isolithocholic acid (0.00003 %) prevents growth of CD196, M68, CF5, 630, and BI9 and significant decreases strains CF5, BI9, M120, and 630 in toxin activity. Isolithocholic acid (0.0003 %) makes that all strains displays a significant decrease in toxin activity, except for R20291 and M120.
In Vivo: The levels of fecal Isolithocholic acid shows obvious decreases from day 28 onward in the high fat diet (HFD) group compared with rats fed a normal diet.
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