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MCE 国际站:Cardiotrophin-1/CTF1 Protein, Human (His)
Cardiotrophin-1/CTF1 Protein, Human (His)是一个大约 25.0 kDa 的人心肌营养因子-1 蛋白,带有 His-flag。Cardiotrophin-1 属于 IL-6 家族,可作为细胞保护分子。
Synonyms: rHuCardiotrophin-1, His; Cardiotrophin-1; CT-1; CTF1
Species: Human
Source: E. coli
研究背景:Cardiotrophin-1 (CT-1) is a new member of the IL-6 family which also includes IL-6, IL-11, leukemia inhibitory factor (LIF), oncostatin M (OSM), and ciliary neurotrophic factor (CNTF).Cardiotrophin-1 induce its biological effects through the shared signaling subunit, gp 130.Human CT-1 encodes a 201 amino acid (aa) residue protein that lacks a hydrophobic signal peptide. Human and mouse CT-1 share 80% aa sequence identity and exhibit cross-species activity. CT-1 is highly expressed in heart, skeletal muscle, liver, lung and kidney. Lower levels of CT-1 expression is also seen in testis and brain.CT-1 initiates downstream signaling pathways through the heterodimerization of gp130 and the LIF receptor beta subunit. A third alpha receptor subunit has been implicated in the receptor complex. Cardiotrophin-1 can acts as a cytoprotective molecule.Recombinant Human Cardiotrophin-1, His is an approximately 25.0 kDa human cardiotrophin-1 protein with a His-flag. Cardiotrophin-1belongs to the IL-6 family and can act as a cytoprotective molecule.
蛋白编号:Q16619 (M1-A201)
基因 ID:1489
产品分类:细胞因子和生长因子 | 神经营养因子 | 心脏营养素-1
Categories:Cytokines and Growth Factors | Neurotrophic Factors | Cardiotrophin-1
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