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MCE 国际站:AIF1 Protein, Mouse (His)
AIF1 Protein, Mouse (His) 是一种肌动蛋白聚合和 Rac1 激活蛋白,可促进血管平滑肌细胞迁移。
Synonyms: Aif1; Iba1Allograft inflammatory factor 1; AIF-1; Ionized calcium-binding adapter molecule 1
Species: Mouse
Source: E. coli
研究背景:Allograft inflammatory factor-1 (AIF-1), which is also known as ionized calcium-binding adapter molecule 1 (Iba1), is a cytoplasmic protein with EF-hand calcium-binding domains and was first observed in the macrophages of rat heart allografts under chronic rejection. AIF-1 is highly expressed in the monocytic lineage, including macrophages and microglia, and is involved in phagocytosis and the formation of membrane ruffling through Rac1, which belongs to the Rho-family of GTPases. AIF-1 is not present in cultured human VSMCs but is induced by cytokines, and overexpression of AIF-1 results in increased VSMC growth and cell-cycle gene expression.
蛋白编号:O70200 (S2-P147)
基因 ID:11629
产品分类:其他
Categories:Others
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