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MCE 国际站:CD19 Protein, Human (CHO, Fc)
CD19 Protein, Human (CHO, Fc)是在 CHO 中产生的 C-末端标记 IgG1 Fc 片段的多肽链。CD19 是正常和肿瘤 B 细胞的生物标志物。
Synonyms: rHuCD19, Fc Chimera; B-lymphocyte surface antigen B4; T-cell surface antigen Leu-12
Species: Human
Source: CHO
研究背景:CD19 is classified as a type I transmembrane protein, with a single transmembrane domain, a cytoplasmic C-terminus, and extracellular N-terminus. CD19 is a biomarker for normal and neoplastic B cells, as well as follicular dendritic cells. CD19 is critically involved in establishing intrinsic B cell signaling thresholds through modulating both B cell receptor-dependent and independent signaling. CD19 functions as the dominant signaling component of a multimolecular complex on the surface of mature B cells, alongside complement receptor CD21, and the tetraspanin membrane protein CD81 (TAPA-1), as well as CD225. Through study of CD19 transgenic and knockout mouse models, it becomes clear that CD19 plays a critical role in maintaining the balance between humoral, antigen-induced response and tolerance induction.
蛋白编号:P15391 (P20-K291)
基因 ID:930
产品分类:CD 抗原 | B 细胞 CD 蛋白 | CD19 | CD 抗原 | 干细胞 CD 蛋白 | CD19 | CD 抗原 | 树突细胞 CD 蛋白 | CD19 | CAR-T 相关蛋白 | CD19
Categories:CD Antigens | B Cell CD Proteins | CD19 | CD Antigens | Stem Cell CD Proteins | CD19 | CD Antigens | Dendritic Cell CD Proteins | CD19 | CAR-T related Proteins | CD19
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