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MCE 国际站:Clusterin/APOJ Protein, Human (HEK293, Fc-His)
Clusterin/APOJ Protein, Human (HEK293, Fc-His)在 HEK293 细胞中表达,N 端带有 Fc 片段和 His 标签。Clusterin/APOJ Protein 参与许多对脂质运输,血管平滑肌细胞分化很重要的生理过程,并具有用于动脉粥样硬化的潜力。
Synonyms: rHuApolipoprotein J, C-Fc-His; ApoJ; Clusterin; CLU; CLI; KUB1; Apolipoprotein J
Species: Human
Source: HEK293
Biological Activity: Measured by its ability to induce clustering of Caki-2 human clear cell carcinoma epithelial cells.
研究背景:Apolipoprotein J (apoJ), also known as clusterin (CLU), which is tightly associated with both lipid and apoAl in HDLs in blood, has been proposed as such biomarker through numerous researches. In the process of relieving atherosclerosis, apoJ can promote cholesterol and phospholipid export from macrophage-foam cells, and exhibit cytoprotective and anti-inflammatory actions by interacting with lots of known inflammatory proteins which may predict the onset of clinical cardiovascular events and may actually play a causal role in mediating atherosclerotic disease such as C-reactive protein, paraoxonase, and leptin.
蛋白编号:P10909 (D23-E449)
基因 ID:1191
产品分类:其他
Categories:Others
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