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MCE 国际站:PVR/CD155 Protein, Human (HEK293, Fc)
PVR/CD155 Protein, Human (HEK293, Fc)是免疫球蛋白超家族中的一种I型跨膜糖蛋白,参与人类动物细胞脊髓灰质炎病毒感染和肠道体液免疫反应。
Synonyms: rHuPVR/CD155, Fc Chimera; Poliovirus receptor; NECL-5; PVS
Species: Human
Source: HEK293
Biological Activity: 1. 5 µg/mL (100 µL/well) of immoblized recombinant human PVR/CD155-Fc can bind human Biotin-TIGIT-Fc with a linear range of 6.1-48.8 ng/mL.
2. Measured by its binding ability in a functional ELISA. Immobilized human CD226, at 2 μg/mL (100 μL/well) can bind Biotinylated human CD155 protein. The ED50 for this effect is 37.33 ng/mL, corresponding to a specific activity is 2.679×10^4 Unit/mg.
研究背景:CD155 is a Type I transmembrane glycoprotein in the immunoglobulin superfamily. Commonly known as Poliovirus Receptor (PVR) due to its involvement in the cellular poliovirus infection in primates, CD155's normal cellular function is in the establishment of intercellular adherens junctions between epithelial cells. The role of CD155 in the immune system is unclear, though it may be involved in intestinal humoral immune responses. CD155 may also be used to positively select MHC-independent T cells in the thymus.
蛋白编号:P15151 (W21-N343)
基因 ID:5817
产品分类:受体蛋白 | 细胞粘附分子 | 免疫球蛋白超家族细胞粘附分子 | PVR/CD155 | CD 抗原 | NK 细胞 CD 蛋白 | PVR/CD155 | CD 抗原 | 巨噬细胞 CD 蛋白 | PVR/CD155 | CD 抗原 | 单核细胞 CD 蛋白 | PVR/CD155 | 免疫检查点蛋白 | 抑制性免疫检查点 | 免疫检查点蛋白 | 刺激性免疫检查点
Categories:Receptor Proteins | Cell Adhesion Molecules (CAMs) | Immunoglobulin-like Cell Adhesion Molecules | PVR/CD155 | CD Antigens | NK Cell CD Proteins | PVR/CD155 | CD Antigens | Macrophage CD Proteins | PVR/CD155 | CD Antigens | Monocyte CD Proteins | PVR/CD155 | Immune Checkpoint Proteins | Inhibitory Checkpoint Molecules | Immune Checkpoint Proteins | Stimulatory Immune Checkpoint Molecules
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