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MCE 国际站:Eotaxin/CCL11 Protein, Mouse
Eotaxin/CCL11 Protein, Mouse是嗜酸性粒细胞、嗜碱性粒细胞和Th2淋巴细胞的有效化学诱导剂。
Synonyms: rMuEotaxin/CCL11; C-C motif chemokine 11; Eosinophil chemotactic protein; SCYA11
Species: Mouse
Source: E. coli
Biological Activity: Full biological activity determined by a chemotaxis bioassay using purified eosinophils is in a concentration range of 100-1000 ng/mL.
研究背景:CCL11 is a small cytokine belonging to the CC chemokine family. CCL11 selectively recruits eosinophils by inducing their chemotaxis, and therefore, is implicated in allergicresponses. It is produced by IFN-γ-stimulated endothelial cells and TNF-activated monocytes. CCL11 is a potent chemoattractant for eosinophils, basophils, and Th2 lymphocytes. CCL11 has a number of important biological functions in disease processes. It plays a critical role in allergic and nonallergic inflammatory reactions, such as mycobacterial and schistosomal induced granulomatosis.
蛋白编号:P48298 (H24-P97)
基因 ID:20292
产品分类:细胞因子和生长因子 | 趋化因子 | CC 趋化因子 | 趋化因子 CCL11
Categories:Cytokines and Growth Factors | Chemokine & Receptors | CC Chemokines | Eotaxin/CCL11
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