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MCE 国际站:Cathepsin L1 Protein, Human (HEK293, His)
Cathepsin L1 Protein, Human (HEK293, His)是一种主要的半胱氨酸蛋白酶,在细胞内蛋白分解代谢中起着重要作用。
Synonyms: rHuCathepsin L1, His; Cathepsin L1; Major Excreted Protein; MEP; CTSL1; CTSL
Species: Human
Source: HEK293
Biological Activity: Biological activity has been tested in vitro.
研究背景:Cathepsin L1, a major cysteine protease secreted by the parasite plays a pivotal role in various aspects of its pathogenicity. For example, Cathepsin L1 takes part in nutrient acquisition by catabolizing host proteins to absorbable peptides, facilitates the migration of the parasite through the host intestine and liver by cleaving interstitial matrix proteins such as fibronectin, laminin, and native collagen, and is implicated in the inactivation of host immune defenses by cleaving immunoglobulins. Cathepsin L1 suppresses Th1 immune responses in infected laboratory animals making them susceptible to concurrent bacterial infections.
蛋白编号:P07711 (T18-V333)
基因 ID:1514
产品分类:酶和调节子 | 组织蛋白酶 | 组织蛋白酶 L1 | 酶和调节子 | 水解酶
Categories:Enzymes & Regulators | Cathepsin | Cathepsin L1 | Enzymes & Regulators | Hydrolases (EC 3)
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