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MCE 国际站:Cathepsin Z/CTSZ Protein, Human (HEK293, His)
Cathepsin X Protein, Human (HEK293, His)是一种溶酶体半胱氨酸蛋白酶,主要存在于单核细胞/巨噬细胞谱系的细胞中。
Synonyms: rHuCathepsin X, His; Cathepsin Z; Cathepsin P; Cathepsin X; CTSZ
Species: Human
Source: HEK293
Biological Activity: The enzyme activity of this recombinant protein is testing in progress, we cannot offer a guarantee yet.
研究背景:Cathepsin X acts as a monocarboxypepidase and has a strict positional and narrower substrate specificity relative to the other human cathepsins. The via activation of β2 integrin receptor Mac-1 (CD11b/CD18) active cathepsin X enhances adhesion of monocytes/macrophages to fibrinogen and regulates the phagocytosis. By activation of Mac-1 receptor cathepsin X may regulate also the maturation of dendritic cells, a process, which is crucial in the initiation of adaptive immunity. Cathepsin X activates also the other β2 integrin receptor, LFA-1 (CD11a/CD18) which is involved in the proliferation of T lymphocytes. The cleavage of C-terminal amino acids of alpha and gamma enolase by cathepsin X abolishes their neurotrophic activity affecting neuronal cell survival and neuritogenesis. Cathepsin X is a cysteine carboxypeptidase, localized predominantly in immune cells, regulating their proliferation, maturation, migration and adhesion.
蛋白编号:Q9UBR2 (G24-V303)
基因 ID:1522
产品分类:酶和调节子 | 组织蛋白酶 | 组织蛋白酶 X | 酶和调节子 | 水解酶
Categories:Enzymes & Regulators | Cathepsin | Cathepsin X/Cathepsin Z | Enzymes & Regulators | Hydrolases (EC 3)
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