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MCE 国际站:CCL6 Protein, Mouse
CCL6 Protein, Mouse 是一种CC趋化因子,仅在啮齿动物中发现,与慢性炎症中的巨噬细胞浸润有关以及在肿瘤发生中起作用。CCL6 Protein, Mouse是一种由 E. coli 表达的重组小鼠CCL6(G22-A116)。
Synonyms: rMuCCL6; C-C motif chemokine 6; Scya6; C10
Species: Mouse
Source: E. coli
Biological Activity: Full biological activity determined by a chemotaxis bioassay using human CCR1 transfected murine BaF3 cells is in a concentration range of 10-100 ng/ml.
研究背景:CCL6, belongs to the CC family of chemokines is located in mouse chromosome 11. CCL6 can be expressed in cells of the neutrophil and macrophage lineage in mice and can be induced in large numbers under conditions suitable for bone marrow cell differentiation. C10/CCL6 shares significant homology with other chemokines, including human MIP-1γ, CC chemokine F-18 (CCF-18), hemofiltrate CC chemokine (HCC-1), and HCC-2. CCL6 is present in a variety of chronic inflammatory disorders including experimental demyelinating diseases, allergic airway inflammation, bleomycin-induced lung fibrosis and chronic peritonitis. CCL6 also can be used as a monocyte chemoattractant in a murine acute peritonitis.
蛋白编号:P27784 (G22-A116)
基因 ID:20305
产品分类:细胞因子和生长因子 | 趋化因子 | CC 趋化因子 | 趋化因子 CCL6
Categories:Cytokines and Growth Factors | Chemokine & Receptors | CC Chemokines | CCL6
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