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IFN-gamma Protein, Mouse

MCE 国际站：IFN-gamma Protein, Mouse

IFN-gamma Protein, Mouse是一种促炎性细胞因子，具有高效的免疫调节功能，同时可抗细胞增殖，抗病毒等。

Synonyms: rMuIFN-γ; IFNG; IFN-gamma; Interferon gamma

Species: Mouse

Source: E. coli

Biological Activity: 1. Determined by its ability to inhibit the proliferation of murine WEHI-279 cells. The expected ED₅₀ is < 1 ng/mL.
2. Measured by its ability to inhibit the proliferation of HT-29 human coloncancer cells. The ED₅₀ for this effect is 0.7283 ng/mL, corresponding to a specific activity is 1.37×10⁶ Unit/mg.

研究背景：Interferon-gamma (IFN-γ) is a cytokine with potent immunomodulatory, anti-proliferative, and antiviral properties. IFN-γ activates cells via a different receptor than IFN-α and IFN-β, which accounts for the different physiological properties of the proteins. Production of IFN-γ is largely restricted to activated CD4⁺ TH1 T cells, CD8⁺ T cells, and natural killer cells. One of the most important consequences of IFN-γ secretion is the activation of macrophages. In addition, IFN-γ plays a central role in inflammatory responses by activating endothelial cells, promoting TH1 cell development and cellular immune responses, and up-regulation of major histocompatability complex protein expression on antigen-presenting cells.

蛋白编号：P01580 (H23-C155)

基因 ID：15978

产品分类：细胞因子和生长因子  |  干扰素  |  干扰素 γ

Categories：Cytokines and Growth Factors  |  Interferon & Receptors  |  IFN-γ

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