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Farrerol

CAS No. : 24211-30-1

MCE 国际站：Farrerol

产品活性：Farrerol 是杜鹃花的一种生物活性成分，具有抗氧化、抗炎、抗肿瘤、神经保护和肝保护等多种作用。

研究领域：Others

作用靶点：Others

结构分类：黄酮类  |  二氢黄酮  |  酚类  |  多酚类

来源：植物  |  杜鹃花科  |  兴安杜鹃

In Vitro: Farrerol observably reduces the production of inflammatory mediators including IL-1β, IL-6, TNF-α, COX-2, and iNOS in LPS-induced RAW264.7 cells via suppressing AKT, ERK1/2, JNK1/2, and NF-κB p65 phosphorylation.
Farrerol attenuates β-amyloid-induced oxidative stress and inflammation through Nrf2/Keap1 pathway in a microglia cell line.
Farrerol inhibits angiogenesis through Akt/mTOR, Erk and Jak2/Stat3 signal pathway.
Farrerol overcomes the invasiveness of lung squamous cell carcinoma cells by regulating the expression of inducers of epithelial mesenchymal transition.
Farrerol ameliorates acetaminophen-induced hepatotoxicity via activation of Nrf2 and autophagy.

In Vivo: Farrerol protects dopaminergic neurons in a rat model of lipopolysaccharide-induced Parkinson's disease by suppressing the activation of the AKT and NF-κB signaling pathways.

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货号: HY-N0344

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