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CAS No. : 1218-98-0
MCE 国际站:7,8-Dihydroneopterin
产品活性:7,8-Dihydroneopterin 是一种炎症标记,通过增强一氧化氮合酶 (iNOS) 的表达来诱导星形胶质细胞和神经元细胞凋亡 (apoptosis)。可用于神经退行性疾病的研究。
研究领域:Apoptosis | Immunology/Inflammation | Metabolic Enzyme/Protease
作用靶点:Apoptosis | NO Synthase | Endogenous Metabolite
结构分类:其他类 | 结构分类
In Vitro: 7,8-Dihydroneopterin is a heterocyclic pteridine which produced and secreted by monocytes/macrophages upon stimulation with the cytokine interferon-y (IFN-y).
7,8-Dihydroneopterin (0.1, 0.5, 1, 2.5, 5 mM; 2 days and 5 days) inhibits growth of U373MG astroeytes .
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