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CAS No. : 53-03-2
MCE 国际站:Prednisone
产品活性:Prednisone (Adasone) 是皮质类固醇试剂,具有抗炎及免疫抑制作用,可用于研究系统性红斑狼疮等相关疾病。
研究领域:Immunology/Inflammation | Vitamin D Related/Nuclear Receptor | Apoptosis
作用靶点:Glucocorticoid Receptor | Apoptosis
In Vivo: Prednisone (intramuscular injection, 10 mg/kg once a day, on days 4 to 13) reduces the survival rate on days lower than the control group in BALB/c mice with encephalomyocarditis virus myocarditis. Besides, myocardial virus titers reaches a maximum on day 4, but there is no antibody titer, and on day 8 virus titers remains elevated and antibody titers is also high. On day 10, antibody titers are significantly lower than controls, while viral titers remains significantly elevated.
Prednisone (5 mg/kg, intragastrically administration, daily) can cause changes in FA metabolism in SLE mouse (MRL/lpr) model.
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货号: HY-B0214
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