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CAS No. : 76-22-2
MCE 国际站:Camphor
产品活性:Camphor ((±)-Camphor) 是一种外用抗感染和抗瘙痒剂,口服有驱风作用。然而,Camphor 摄入时有毒。Camphor 具有抗病毒,镇咳和抗癌活性。Camphor 是一种 TRPV3 激动剂。
研究领域:Membrane Transporter/Ion Channel | Neuronal Signaling | Anti-infection
作用靶点:TRP Channel | Influenza Virus
结构分类:萜类 | 其他单萜 | 结构分类
来源:植物 | 樟科 | 樟树
In Vitro: Camphor induces fibroblast proliferation through the PI3K/AKT and ERK signaling pathways.
The MTT assay results show that 32.5, 65, 130, and 260 μM Camphor increase fibroblast viability to 108.9±6.6%, 118.6±2.8%, 127.7±4.2%, and 131.6±7.2%, respectively, compared to 0 μM Camphor treatment.
Camphor (0-260 μM) treatment for 24 hours increases the generation of ROS by up to 17.97% compared to 5.04% in the no-treatment control.Camphor (0-260 μM, 24 hours) induces the phosphorylation of PI3K, AKT, ERK, and 4EBP1 in a dose- and time-dependent manner.
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