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CAS No. : 25990-10-7
MCE 国际站:Polygalacturonic acid
产品活性:Polygalacturonic acid (Galacturonic acid polymer) 是透明胶状酸,是细胞壁的主要成分。Polygalacturonic acid 可用于制备银纳米颗粒 (AgNPs),作为抗氧化剂和抗炎剂,保护细胞免受 ROS 升高的破坏作用,并加速伤口愈合。Polygalacturonic acid 纳米颗粒也表现出抗菌活性。
研究领域:Others
作用靶点:Others
结构分类:糖类 | 多糖 | 其他类 | 结构分类
来源:植物 | 蔷薇科 | 苹果
In Vitro: Polygalacturonic acid can be used to format a durable hydrogel, to prolong the effect of drugs. Polygalacturonic acid hydrogel/hyaluronate, conjugated Ibuprofen (HY-78131) for example, prevents epidural fibrosis, the severe scar tissue adhesion of laminectomized male adult rats, and increases the efficiency of local inflammation control and reduces the side-effect of Ibuprofen.
Polygalacturonic acid hydrogel/hyaluronate (PGA-HA) (2%, 200 μL; 24 h) shows low cytotoxicity on L929 fibroblasts.
Polygalacturonic acid (PGA) preparing (Ag-PGA/HA)-PVA nanoparticles, shows anti-bacterial activity against gram-positive bacterial strains; Bacillus Subtilis and Staphylococcus Aureus, as well as gram-negative bacterial strain; Escherichia Coli.
In Vivo: Polygalacturonic acid (external application; 14 d) enhances a quick healing of wound infection in albino rats.
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货号: HY-N6613
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