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Clovamide

CAS No. : 53755-02-5

MCE 国际站：Clovamide

产品活性：Clovamide (trans-Clovamide) 是一种天然酚类化合物，是一种有效的抗氧化剂。Clovamide 是一种极好的 ROS 和氧自由基清除剂。Clovamide 还具有抗炎和神经保护作用。Clovamide 是一种抗微生物剂，具有抗人类病原体 A 型流感亚型 H5N1、Trypanosoma evansi 和 Heliobacter pylori 的活性。

研究领域：Immunology/Inflammation  |  NF-κB  |  Metabolic Enzyme/Protease  |  Anti-infection  |  Apoptosis

作用靶点：Reactive Oxygen Species  |  Bacterial  |  Influenza Virus  |  Apoptosis

结构分类：酚类  |  多酚类  |  生物碱

来源：植物  |  其他科

In Vitro: Clovamide is able to protect neurons from injury in three in vitro models of neuronal death: oxidative stress, excitotoxicity and OGD/reoxygenation. In SH-SY5Y human neuroblastoma cells, Clovamide (10-100 µM) significantly protects cell death, with an EC50 value of 3.6 µM. Clovamide also significantly enhances PPARγ expression.
Clovamide inhibits growth of three pathogens of cacao in the genus Phytophthora, is a substrate for cacao polyphenol oxidase, and is a contributor to enzymatic browning. Clovamide inhibiteds proteinase and pectinase in vitro.

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