MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务。

1-Benzylimidazole

CAS No. : 4238-71-5

MCE 国际站：1-Benzylimidazole

产品活性：1-Benzyl-1H-imidazole 是一种生化试剂，可作为生物材料或有机化合物，用于生命科学相关研究。

研究领域：Others

作用靶点：Biochemical Assay Reagents

In Vitro: Benzylimidazole is a selective inhibitor of thromboxane synthase and a stimulator of UDP-glucuronosyltransferase. Thromboxane synthase is a cytochrome P450 enzyme. The cytochrome P450 proteins have been involved in catalyzing many reactions invol ved in drug metabolism and synthesis of cholesterol, steroids , and other lipids. The enzyme plays an important role in several pathophysiological processes including hemostasis, cardiovascular disease, and stroke. The gene expresses two transcript variants. 1-Benzylimidazole selectively inhibited the activity of thrombus Boxane synthase. 1-Benzylimidazole reduced TXB2 levels and increased blood flow in ischemia-reperfusion injury of rat brain. In male Wistar rats, gastrically administration of 1-benzylimidazole (25, 75 and 100 mg/kg/day) caused a dose-dependent hepatitis. 1-Benzylimidazole decreased the plasma level in triglycerides by 60–70%. 1-benzylimidazole stimulated three distinct forms of UDP-glucuronosyltransferase. 1-benzylimidazole significantly increased the activities towards 4-methylumbelliierone, 1-naphthol, morphine or a monoterpenoid alcohol, nopol. Benzylimidazole increased hepatocellular CYP1A catalytic activity and CYP1A mRNA in a concentration-dependent way.

相关产品：Levoglucosenone  |  HPMC (Type I,Viscosity:400mPa.s)  |  Maltotriose hydrate  |  Methyl β-D-arabinopyranoside  |  Methyl 12-aminododecanoate hydrochloride  |  Methyl undec-10-enoate  |  DDMAB  |  Allyl heptanoate  |  Octyl α-D-glucopyranoside  |  Nonyl-β-D-1-thiomaltoside  |  trans-2-Undecenal  |  4-Nitrophthalonitrile  |  Homobrassinolide  |  2-Chloronicotinaldehyde  |  Orange G  |  2,5-Dibromothiazole  |  (Boc-aminooxy)acetic acid  |  Tetrahexylammonium bromide  |  4-(Diphenylamino)benzeneboronic acid  |  FITC-Dextran (MW 110000)  |  Anti-inflammatory agent 43  |  Arachidonoyl thio-PC  |  3-(Trifluoromethyl)phenyltrimethylammonium iodide  |  Murapalmitine  |  6-Amino-1-hexanol  |  Adenosine 3'-phosphate 5'-phosphosulfate lithium  |  (4-Boc-aminophenyl)boronic acid  |  Fluorol Yellow 088  |  Sodium carboxymethyl cellulose (Viscosity:300-800mpa.s)  |  Malic acid disodium salt

热门产品线：重组蛋白  |  化合物库  |  天然产物  |  荧光染料  |  PROTAC  |  同位素标记物  |  寡核苷酸  |  抗体  |  点击化学

Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  |  Natural Products  |  Fluorescent Dye  |  PROTAC  |  Isotope-Labeled Compounds  |  Oligonucleotides  |  Antibodies  |  Click Chemistry

货号: HY-W042985

品牌介绍:
•   MCE (MedChemExpress) 拥有200 多种全球独家化合物库，我们致力于为全球科研客户提供前沿最全的高品质小分子活性化合物；
•   50,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领；
•   产品种类涵盖各种重组蛋白，多肽，常用试剂盒 ，更有 PROTAC、ADC 等特色产品，广泛应用于新药研发、生命科学等科研项目；
•   提供虚拟筛选，离子通道筛选，代谢组学分析检测分析，药物筛选等专业技术服务；
•   设有专业的实验中心和严格的质控、验证体系；
•   提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；
•   产品的生物活性多经各国客户实验验证；
•   Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；
•   专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；
•   与世界各大制药公司及知名科研机构建立了长期的合作。