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MCE 国际站:IL-23R Protein, Human (353a.a, HEK293, Fc)
Synonyms: Interleukin 23 receptor; IL 23R; IL-23 receptor; IL-23R
Species: Human
Source: HEK293
Biological Activity: 1. Measured by its binding ability in a functional ELISA. Immobilized human IL23A-His+IL12B-His at 10 μg/mL (100 μl/well) can bind human IL23R-Fc and the EC50 is 0.28-0.66 μg/mL.
2. Measured by its binding ability in a functional ELISA. Immobilized mouse IL12Bh (m)+mIL23Ah at 10 μg/mL (100 μl/well) can bind human IL23R-Fc. The EC50 of human IL23R-Fc is 0.14-0.35 μg/mL.
3.Measured in a cell proliferation assay using M-NFS-60 cells. The ED50 this effect is 0.9517 μg/mL, corresponding to a specific activity is 1.05×103 units/mg in the presence of 0.125 ng/mL of recombinant human G-CSF.
4. Measured by its ability to inhibit IL-23 induced IL-17 secretion by Jurkat cells. The ED50 for this effect is 0.03289 μg/mL in the presence of 1 ng/mL IL-23, corresponding to a specific activity is 3.04×10^4 U/mg.
蛋白编号:AAM44229.1 (G24-D353)
基因 ID:149233
产品分类:细胞因子和生长因子 | 白细胞介素 | 白细胞介素-23 受体
Categories:Cytokines and Growth Factors | Interleukin & Receptors | IL-23 Receptor
货号: HY-P73196
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