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IL-3 Protein, Human

MCE 国际站：IL-3 Protein, Human

IL-3 Protein, Human是一种造血细胞因子，对血小板和中性粒细胞计数具有良好效果，对继发性造血功能衰竭具有治疗效果。

Synonyms: rHuIL-3; Hematopoietic growth factor; Mast cell growth factor; MCGF; Multipotential colony-stimulating factor; P-cell-stimulating factor

Species: Human

Source: E. coli

Biological Activity: The ED₅₀ is <0.5 ng/mL as measured by TF-1 cells, corresponding to a specific activity of >2 × 10⁷ units/mg.

研究背景：Interleukin-3 (IL-3) is aglycoprotein belonging to the hematopoietic growth factor family that in preclinical in vitro and in vivo studies has exhibited a multilineage activity. Recombinant human interleukin-3 (rhIL-3) enhances the mobilization of peripheral blood progenitor cells by recombinant human granulocyte colony-stimulating factor (rhG-CSF). Human interleukin-3 (hIL-3) is a multipotent hematopoietic cytokine produced by mitogen and antigen-activated keratinocytes, T-lymphocytes, mast cells, NK cells, monocytes and endothelial cells. The hematopoietic progenitor cells are proliferated and differentiated with the help of hIL-3 protein into mature erythrocytes, mast cells, megakaryocytes and granulocytes. The potential use of hIL-3 protein has been extensively tested in various clinical applications such as bone marrow transplantation, hematological malignancies, cytopenias, aplastic anemia and various types of cancer.

蛋白编号：P08700 (A20-F152)

基因 ID：3562

产品分类：细胞因子和生长因子  |  集落刺激因子  |  多能集落刺激因子

Categories：Cytokines and Growth Factors  |  CSF & Receptors  |  Multi-CSF/IL-3

货号: HY-P7040

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