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MCE 国际站:IL-7 Protein, Mouse (CHO)
IL-7 Protein, Mouse (CHO)由来自骨髓和胸腺细胞产生,在 B 细胞淋巴细胞生成和 T 细胞稳态中起关键作用。
Synonyms: rMuIL-7; LP-1; pre-B cell factor
Species: Mouse
Source: CHO
Biological Activity: The ED50 is <0.4 ng/mL as measured by 2E8 cells.
研究背景:Interleukin-7 (IL-7) is a nonredundant cytokine produced by nonlymphoid cells that is essential for T-cell development in humans and mice and B-cell development in mice. IL-7 contributes to the maintenance of the size and subset composition of the peripheral T-cell pool by providing growth and survival signals through the IL-7 receptor. The IL-7 receptor has a private α-chain and shares the common γ-chain (γc) with other common cytokine receptor users, such as IL-2, IL-4, IL-15, and IL-21. IL-7 together with these cytokines regulates the expansion and contraction of adaptive immune responses and potentially the memory response to a given antigen. IL-7 modulates memory CD8+ T cells in response to a virus infection and, given in conjunction with adoptive transfer of T cells after herpes simplex virus type 1 infection, improves virus clearance.
蛋白编号:P10168 (E26-I154)
基因 ID:16196
产品分类:细胞因子和生长因子 | 白细胞介素 | 白细胞介素-7
Categories:Cytokines and Growth Factors | Interleukin & Receptors | IL-7
货号: HY-P7082
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