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MCE 国际站:Adiponectin/Acrp30 Protein, Mouse (HEK293, His)
Adiponectin/Acrp30 Protein, Mouse (HEK293, His)是脂肪细胞分泌的最丰富的肽,其减少在肥胖相关疾病,包括胰岛素抵抗/ 2型糖尿病和心血管疾病中起核心作用。
Synonyms: rMuAdiponectin, His; Acrp30; ADIPOQ
Species: Mouse
Source: HEK293
Biological Activity: Measured by its ability to inhibit glucose production by rat hepatocytes. The IC50 for this effect is 0.4891 μg/mL, corresponding to a specific activity is 2.044×103 units/mg.
研究背景:Adiponectin has direct actions in liver, skeletal muscle, and the vasculature.Adiponectin exists in the circulation as varying molecular weight forms, produced by multimerization. Several endoplasmic reticulum ER-associated proteins, including ER oxidoreductase 1-α (Ero1-α), ER resident protein 44 (ERp44), disulfide-bond A oxidoreductase-like protein (DsbA-L), and glucose-regulated protein 94 (GPR94), have recently been found to be involved in the assembly and secretion of higher-order adiponectin complexes. Adiponectin administration in humans and rodents has insulin-sensitizing, anti-atherogenic, and anti-inflammatory effects, and, in certain settings, also decreases body weight.
蛋白编号:Q60994 (E18-N247)
基因 ID:11450
产品分类:细胞因子和生长因子 | 肽激素和神经肽 | 脂联素
Categories:Cytokines and Growth Factors | Peptide Hormone & Neuropeptides | Adiponectin
货号: HY-P7461
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