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MCE 国际站:VEGF165 Protein, Human (P.pastoris)
VEGF165 Protein, Human (P.pastoris)是血管内皮生长因子A (VEGF-A) 的亚型。 VEGF是血管内皮细胞特异性的肝素结合生长因子,能够诱导血管生成。
Synonyms: VEGF-AA; rHuVEGF165; VPF; Folliculostellate cell-derived growth factor; Glioma-derived endothelial cell mitogen
Species: Human
Source: P. pastoris
Biological Activity: The ED50 is 1-5 ng/mL as measured by HUVEC cells, corresponding to a specific activity of 2 × 105 - 1 × 106 units/mg.
研究背景:Vascular Endothelial Growth Factor (VEGF) has multiple isoforms, created by alternative splicing or proteolytic cleavage, and characterized by different receptor-binding and matrix-binding properties. These isoforms are known to give rise to a spectrum of angiogenesis patterns marked by differences in branching, which has functional implications for tissues. VEGF-A is a key member of the VEGF family of cytokines, along with VEGF-B, -C, -D, and PlGF. VEGF-A mediates angiogenesis, the expansion of an existing vascular bed by sprouting of new blood vessels. The vegfa gene is translated into a number of splice isoforms, the most notable in humans being VEGF121, VEGF165, and VEGF189.
蛋白编号:P15692-4 (A27-R191)
基因 ID:7422
产品分类:细胞因子和生长因子 | 血管内皮生长因子及受体 | 血管内皮生长因子 | 血管内皮生长因子 A
Categories:Cytokines and Growth Factors | VEGF & VEGFR | VEGF | VEGF-A
货号: HY-P7110
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