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Acumapimod

CAS No. : 836683-15-9

MCE 国际站：Acumapimod

产品活性：Acumapimod (BCT197) 是口服活性的p38 MAP激酶抑制剂，对p38α的IC₅₀值小于1 μM。

研究领域：MAPK/ERK Pathway  |  Autophagy

作用靶点：p38 MAPK  |  Autophagy

In Vitro: Acumapimod is an inhibitor of p38α with an IC₅₀ value of less than 1 μM.

In Vivo: Acumapimod is an oral low-molecular-weight p38 inhibitor currently in development for the treatment of several inflammatory conditions, including chronic obstructive pulmonary disease (COPD). Intermittent short-term dosing of Acumapimod (75 mg on days 1 and 6) shows a marked improvement in lung function in COPD patients.

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