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CAS No. : 313348-27-5
MCE 国际站:Regadenoson
产品活性:Regadenoson (CVT-3146) 是一种选择性的 A2A 腺苷受体激动剂和血管扩张剂,能增加冠状动脉血流量,可用于心肌灌注成像的研究。Regadenoson 还能增加啮齿动物血脑屏障 (BBB) 的通透性,可用于增加人类中枢神经系统活性分子输送的研究。
研究领域:GPCR/G Protein
作用靶点:Adenosine Receptor
In Vivo: Regadenoson (0.1, 0.175, 0.25, 0.5, 1.0, 2.5, 5 μg/kg; p.i.v.; single) increases coronary blood flow (CBF) and decreases in mean coronary resistance in a dose-dependent manner, in awake dogs.
?Regadenoson (2.5 μg/kg; p.i.v.; single in 30 s) increases blood flow of coronary in awake dogs.
?Regadenoson (0.5 μg/kg; i.v.; single; 60 or 90 min after Temozolomide administration) promotes Temozolomide delivery to CNS of rats.
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货号: HY-A0168
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