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Tipiracil

CAS No. : 183204-74-2

MCE 国际站：Tipiracil

产品活性：Tipiracil 是一种胸苷磷酸化酶 (TPase) 抑制剂。

研究领域：Apoptosis  |  Cell Cycle/DNA Damage

作用靶点：Thymidylate Synthase  |  Nucleoside Antimetabolite/Analog

In Vitro: Tipiracil is an inhibitor of thymidine phosphorylase. Tipiracil increases trifluridine exposure by inhibiting its metabolism by thymidine phosphorylase. The combination of Trifluridine and Tipiracil is a new oral treatment for metastatic colorectal cancer. Tipiracil prevents degradation of FTD through a first-pass effect as a thymidine phosphorylase inhibitor.

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