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Argatroban monohydrate

CAS No. : 141396-28-3

MCE 国际站：Argatroban monohydrate

产品活性：Argatroban (monohydrate) (MD-805 (monohydrate)) 是 thrombin 选择性抑制剂。

研究领域：Metabolic Enzyme/Protease

作用靶点：Thrombin

In Vitro: Argatroban (MD-805) may have a complementary effect for preventing thrombus formation without aggravating bleeding tendency because of its monotarget specificity to thrombin. Administration (0.5 to 2 micrograms/kg/min) of Argatroban (MD-805) is a safe anticoagulant for left heart bypass in repairs of traumatic aortic rupture associated with multiple organ injuries. Argatroban (MD-805), as compared with heparin, appears to enhance reperfusion with TPA in patients with AMI, particularly in those patients with delayed presentation. The incidences of major bleeding and adverse clinical outcome were lower in the patients receiving argatroban.

In Vivo: Argatroban monohydrate can be used in animal modeling to create a model of endogenous intestinal plugs.

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