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CAS No. : 579-38-4
MCE 国际站:Diloxanide
产品活性:Diloxanide 是一种抗原虫制剂 (anti-protozoal agent),可用于组织学内阿米巴原虫或者其他原虫感染引起的无症状肠道阿米巴病的研究。Diloxanide 是一种活性的鲁米那抗阿米巴试剂,在胃肠道中,由其前体二氯尼特糠酸酯 (HY-B1147) 水解得来。
研究领域:Anti-infection
作用靶点:Parasite
In Vivo: Diloxanide is hydrolyzed in the gastrointestinal tract from its prodrug Diloxanide furoate.Diloxanide furoate (oral administraion; 75-200 mg/kg; 3 days; once daily) is effective at different dose of dayin weanling rats. At 200 mg/kg, 100% of the treated rats are cured and no amoebic lesions are observed in the caecum. Besides, 85%,77%, and 44.4% of the treated rats are cured at the dose 150 mg/kg, 100 mg/kg, and 75 mg/kg, respectively. The ED50 value is 77.9 mg/kg for this agent in rats.
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货号: HY-119972
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