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CAS No. : 934358-00-6
MCE 国际站:TBCA
产品活性:TBCA 是一种高选择性的酪蛋白激酶II CK2 抑制剂,IC50 为 110 nM,Ki 为 77 nM。TBCA 对 CK1、DYRK1A 和 其它 27 个激酶表现出选择性。
研究领域:Cell Cycle/DNA Damage | Stem Cell/Wnt
作用靶点:Casein Kinase
In Vitro: TBCA (0-100 μM; 24 hours) shows a drastic effect on Jurkat cells viability.
TBCA also inhibits CK2 double mutant (Val66 Ile174) with an IC50 of 0.68 μM.
TBCA dose-dependently inhibits platelet aggregation and secretion induced by various agonists including 2-MeSADP, AYPGKF, SFLLRN, and CRP. TBCA also inhibits phosphorylation of PDK1, Akt, and GSK3β induced by AYPGKF.
相关产品:Bioactive Compound Library Plus | Cell Cycle/DNA Damage Compound Library | Kinase Inhibitor Library | Stem Cell Signaling Compound Library | Wnt/Hedgehog/Notch Compound Library | Anti-Cancer Compound Library | Anti-Aging Compound Library | Targeted Diversity Library | Cancer Stem Cells Compound Library | Membrane Protein-targeted Compound Library | Highly Selective Inhibitors Library | CK2-IN-4 | Umbralisib hydrochloride | 4,5,6,7-Tetrabromo-1H-benzimidazole | JNJ-6204 | CK2-IN-1 | PF-5006739 | TA-01 | Ellagic acid | EGFR-IN-57 | AMG-548 hydrochloride | CKI-7 free base | SR-1277 | CK2α-IN-1 | NCC007 | Emodin-d4 | Casein Kinase II Inhibitor IV | TMX-4113 | BTX161 | D4476 | Casein Kinase II Receptor Peptide | PI-828 | CK2 inhibitor 2 | TTP 22 | Longdaysin | CK2/ERK8-IN-1 | TMCB | Silmitasertib sodium salt
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货号: HY-110052
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