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CAS No. : 1118807-13-8
MCE 国际站:KY02111
产品活性:KY02111 是一种典型的 WNT 信号 (WNT signaling/β-catenin) 抑制剂,可促进人多潜能干细胞向心肌细胞分化。KY02111 可用于人类心肌细胞再生的研究。
研究领域:Stem Cell/Wnt
作用靶点:Wnt
In Vitro: KY02111 promotes differentiation by inhibiting WNT signaling in hPSCs.
KY02111 induces cardiomyocytes expressed the cardiac markers, αMHC, NKH2.5, and HCN4.
KY02111 (1-10 μM; 12 hours, 24 hours) reduces WNT signaling in both IMR90-1 cells and HEK293 cells in a dose-dependent manner.
KY02111 treatment with WNT signaling modulators produces robust cardiac differentiation of hPSCs in a xeno-free, defined medium, devoid of serum and any kind of recombinant cytokines and hormones, such as BMP4, Activin A, or insulin.
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货号: HY-13815
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