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CAS No. : 2447-57-6
MCE 国际站:Sulfadoxine
产品活性:Sulfadoxine(Sulphadoxine)是长效的磺胺类化合物,常与pyrimethamine结合起到抗疟疾作用。Sulfadoxine 抑制 HIV 在外周血单核细胞中的复制。
研究领域:Anti-infection | Metabolic Enzyme/Protease
作用靶点:Parasite | HIV | Antibiotic | Endogenous Metabolite
In Vitro: Sulfadoxine(Sulphadoxine) is an ultra-long-lasting sulfonamide. Sulfadoxine is often used in combination with pyrimethamine to treat or prevent malaria. Both drugs are antifolates; they inhibit the production of enzymes involved in the synthesis of folic acid within the parasites. Either drug by itself is only moderately effective in treating malaria, because the parasite Plasmodium falciparum may be able to use exogenous folic acid, i.e. folic acid which is present in the parasite's environment, while in combination, the two substances have a synergistic effect which outbalances that ability [1, 2].
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货号: HY-B0439
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