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BIZ 114

CAS No. : 2099120-74-6

MCE 国际站：BIZ 114

产品活性：BIZ 114 (Example 11) 是一种脂肪酸衍生物，可有效抑制 TNF-α 激活的 NF-κΒ 途径。BIZ 114 可用于眼科疾病（例如视网膜退行性疾病和眼部炎症性疾病）的研究。

研究领域：NF-κB

作用靶点：NF-κB

In Vitro: Polyunsaturated fatty acids and their metabolites are involved in many physiological and pathophysiological reactions and as such possess a range of important biological activities. They affect plasma lipids and lipid metabolism. They are incorporated into cell membranes where they influence different cell functions. They are also involved in inflammatory diseases and they also influence and control gene expression. The fatty acid derivatives have the potential for treatment and/or prevention of ophthalmic disorders, in particular retinal disorders such as age-related macular degeneration and diabetic retinopathy, and ocular inflammatory diseases.

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