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AKT Kinase Inhibitor hydrochloride

CAS No. :

MCE 国际站：AKT Kinase Inhibitor hydrochloride

产品活性：AKT Kinase Inhibitor hydrochloride 是一种具有抗肿瘤活性的 Akt 抑制剂。

研究领域：PI3K/Akt/mTOR

作用靶点：Akt

In Vitro: The effect of selective inhibition of Akt in proliferating cells expressing Trop-2 is studied. Akt inhibition, either by silencing or with specific drugs, induces a marked decrease in cell proliferation in cells expressing Trop-2, in a dose-dependent fashion.

In Vivo: Trop-2 expressing tumors subcutaneously injected in animal models show a striking reduction of growth following treatment with specific drugs that inhibit Akt activity. Therefore Akt has a central functional role in mediating the Trop-2-dependent growth stimulus.

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货号: HY-10249D

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